A systems biology approach to study the Influenza virus

Funded by the National Institute of Allergy and Infectious Diseases, we are composed of a highly diverse team of investigators throughout the US. We propose a systematic approach (FluOMICS) to generate predictive models of influenza virus pathogenesis which will a) allow us to identify biomarkers for predicting pathogenic potential of new influenza viruses, b) give us the ability to predict which populations may be more susceptible to disease based on genetic variability, and c) provide avenues to explore for new, host-directed, therapeutic interventions.